About

The ANTARES lab at McLean Hospital conducts research on social, cognitive, and affective processes in psychopathology and resilience, with our work currently focusing on stress and trauma, reward processing, and social engagement. Broadly, our group is interested in changes in affective, cognitive, and social processing in people who have been exposed to stress, trauma, and/or childhood maltreatment, including individuals with posttraumatic stress disorder (PTSD).

Research

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SATURN Study (ages 16-20) on social behavior following trauma exposure

In this research study we want to learn more about factors that affect social functioning during the transition to adulthood (ages 16-20). Some people who have been exposed to trauma, but not others, struggle to maintain and grow their social relationships. We are hoping to identify a set of factors that help to predict which individuals struggle socially. These may include aspects of the way the brain processes information.

Want to participate? Learn more or sign up.

This study is funded by NIMH R01 MH125852 (PI: Olson).

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Neuroimaging of reward processing in women exposed to assault

The purpose of this study is to identify brain mechanisms and stress peptides (hormones) that may contribute to changes in social functioning in women who have been exposed to physical or sexual assault.

We are no longer enrolling new participants for this project.

This study is funded by NIMH K23 MH112873 (PI: Olson).

STress and Resilience in Prenatal Partners (STRiPP)

The purpose of this study is to monitor stress in partners of women experiencing high-risk pregnancies. We know that people differ in their response to stress. We hope to identify factors that predict how stress responses change over time.

Want to participate? Sign up.

This study is funded by a McLean Hospital Presidential Award (PI: Olson).

People

Our lab is part of the Center for Depression, Anxiety and Stress Research.

I also am a co-investigator in the SPARED Conte Center.

PRINCIPAL INVESTIGATOR:

POSTDOCTORAL FELLOWS:

STEVEN GRANGER, PHD

RESEARCH ASSISTANTS:

Brian Lynch, BA

STUDENTS:

ELIZABETH WANG

ACADEMIC CREDIT AND SENIOR THESIS STUDENT (Harvard College)

SUBUL AHMAD

Undergraduate student visitor, Harvard College

GROUP ALUMNI:

CAROLINE OSTRAND, BA

WAS: RESEARCH ASSISTANT

NOW: GRADUATE STUDENT, UNIVERSITY OF MINNESOTA CLINICAL SCIENCE & PSYCHOPATHOLOGY RESEARCH PROGRAM

WAS: RESEARCH ASSISTANT

NOW: MEDICAL STUDENT, UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE

ASEELAH ASHRAF

Undergraduate Student Visitor (Harvard College)

Undergraduate student visitor, MMHRSP (WESTFIELD STATE UNIVERSITY). NOW: Research assistant, McLean Hospital

WAS: Undergraduate student visitor (BOSTON COLLEGE)

NOW: MEDICAL SCRIBE

BLAIR CHASE

Undergraduate Student Visitor, MMHRSP (AMHERST College)

COLLABORATORS:

Isabelle Rosso

Diego Pizzagalli

Kerry Ressler

Scott Rauch

Christian Webb

Boyu Ren

Lisa Nickerson

Justin Baker

Selected Manuscripts

[For complete bibliography, see NCBI

2022

Folorunso O, Burns White K, Alonso-Caraballo Y, Nowicki G, Olson EA, Pizzagalli DA, Carlezon W, Ressler K, Chartoff E. Building and intentional and impactful summer research experience to increase diversity in mental health research. Neuropsychopharmacology. 2022 Oct.

Hanuka S*, Olson EA*, Admon R, Webb CA, Killgore WDS, Rauch SL, Rosso IM#, Pizzagalli DA#. Reduced anhedonia following internet-based cognitive behavioral therapy for depression is mediated by enhanced reward circuit activation. Psychological Medicine, 2022 Jun 17;1-10. * equal first author # equal last author.

Rosso IM, Silveri MM, Olson EA, Jensen JE, Ren BR. Regional specificity and clinical correlates of cortical GABA alterations in posttraumatic stress disorder. Neuropsychopharmacology. 2022 Apr;47(5):1055-1062. PubMed PMID: 34675380; PubMed Central PMCID: PMC8938424.

2021

Olson EA, Pizzagalli DA, Rosso IM. Social Anhedonia is Associated with Low Social Network Diversity in Trauma-Exposed Adults. J Trauma Stress. 2020 Aug 20;. doi: 10.1002/jts.22577. [Epub ahead of print] PubMed PMID: 32816343; NIHMSID:NIHMS1623295.

2020

Olson EA, Overbey TA, Ostrand CG, Pizzagalli DA, Rauch SL, Rosso IM. Childhood maltreatment experiences are associated with altered diffusion in occipito-temporal white matter pathways. Brain Behav. 2020 Jan;10(1):e01485. doi: 10.1002/brb3.1485. Epub 2019 Nov 26. PubMed PMID: 31773917; PubMed Central PMCID: PMC6955831.

2019

Olson EA, Kaiser RH, Pizzagalli DA, Rauch SL, Rosso IM. Regional Prefrontal Resting-State Functional Connectivity in Posttraumatic Stress Disorder. Biol Psychiatry Cogn Neurosci Neuroimaging. 2019 Apr;4(4):390-398. doi: 10.1016/j.bpsc.2018.09.012. Epub 2018 Oct 4. PubMed PMID: 30449518; PubMed Central PMCID: PMC6447465.

2018

Olson EA, Kaiser RH, Pizzagalli DA, Rauch SL, Rosso IM. Anhedonia in Trauma-Exposed Individuals: Functional Connectivity and Decision-Making Correlates. Biol Psychiatry Cogn Neurosci Neuroimaging. 2018 Nov;3(11):959-967. doi: 10.1016/j.bpsc.2017.10.008. Epub 2017 Nov 16. PubMed PMID: 30409390; PubMed Central PMCID: PMC6233731.

Webb CA, Olson EA, Killgore WDS, Pizzagalli DA, Rauch SL, Rosso IM. Rostral Anterior Cingulate Cortex Morphology Predicts Treatment Response to Internet-Based Cognitive Behavioral Therapy for Depression. Biol Psychiatry Cogn Neurosci Neuroimaging. 2018 Mar;3(3):255-262. doi: 10.1016/j.bpsc.2017.08.005. Epub 2017 Aug 26. PubMed PMID: 29486867; PubMed Central PMCID: PMC6005352.

2017

Olson EA, Cui J, Fukunaga R, Nickerson LD, Rauch SL, Rosso IM. Disruption of white matter structural integrity and connectivity in posttraumatic stress disorder: A TBSS and tractography study. Depress Anxiety. 2017 May;34(5):437-445. doi: 10.1002/da.22615. Epub 2017 Mar 15. PubMed PMID: 28294462; PubMed Central PMCID: PMC5407943.

News

December 2022: We are planning to hire a full-time RA to run the SATURN study, beginning in summer 2023. Apply here. For additional guidance on application materials, look here.

September 2022: Welcome Steve! Steven Granger, PhD has joined the lab as a postdoctoral fellow. 

August 2022: Congrats to Blair! Blair Chase has received a travel award to SACNAS to present the work that he did in the lab as part of the MMHRSP.

August 2022: Goodbye and congratulations to Caroline Ostrand, who is off to work on her PhD at the University of Minnesota’s Clinical Science and Psychopathology Research Program.

Contact

eaolson@mclean.harvard.edu

617-855-2268

115 Mill St., Mailstop 334
Belmont, MA  02478